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c-erbb-2 antibody  (Thermo Fisher)


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    Structured Review

    Thermo Fisher c-erbb-2 antibody
    C Erbb 2 Antibody, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/c-erbb-2+antibody/c+erbb+2+antibody/pm38909139-36-19-21
    Average 90 stars, based on 1 article reviews
    c-erbb-2 antibody - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Immunohistochemical staining:

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of the cell blocks after deparaffinization and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific) at a 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.
    Article Snippet: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/ neu expression DennisMauricio , Stefania Bellone , LeventMutlu , BlairMcNamara , DiegoD.Manavella , CemDemirkiran , Miguel Skyler Z. Verzosa , Natalia Buza , Pei Hui , Tobias Max Philipp Hartwich , Justin Harold , Yang Yang-Hartwich , Margherita Zipponi , Gary Altwerger , Elena Ratner , Gloria S. Huang , Mitchell Clark , Vaagn Andikyan , Masoud Azodi , Peter E. Schwartz , Alessandro D. Santin a,⁎

    Article Title: Narrative review on the evolving role of HER2/neu targeting in uterine serous cancers
    Article Snippet: Tymon-Rosario et al ., 2021 ( ) , 12 USC cell lines , Thermo Fisher Scientific c-erbB-2 antibody , Modified 2007 ASCO/CAP; positive: 3+; equivocal 2+; negative: 0/1+ , 16.7% (2/12) , 25.0% (3/12) , , PathVysion HER2 DNA Probe Kit , Modified ASCO/CAP breast [2007] ( ) , 25.0% (3/12) , Not reported.

    Article Title: Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression
    Article Snippet: Briefly, HER2/neu immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2.
    Article Snippet: In the United States, epithelial ovarian (EOC), fallopian tube, and primary peritoneal cancer represent the leading cause of death from gynecologic malignancy.. In 2024, there will be a projected 19,680 new cases and 12,740 resultant deaths in the United States alone [1].. Due in part to a lack of adequate screening tests and non-specific symptoms, over two-thirds of ovarian, fallopian tube, or primary peritoneal cancers are diagnosed at an advanced/metastatic stage (III or IV) [2].

    Staining:

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of the cell blocks after deparaffinization and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific) at a 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.
    Article Snippet: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/ neu expression DennisMauricio , Stefania Bellone , LeventMutlu , BlairMcNamara , DiegoD.Manavella , CemDemirkiran , Miguel Skyler Z. Verzosa , Natalia Buza , Pei Hui , Tobias Max Philipp Hartwich , Justin Harold , Yang Yang-Hartwich , Margherita Zipponi , Gary Altwerger , Elena Ratner , Gloria S. Huang , Mitchell Clark , Vaagn Andikyan , Masoud Azodi , Peter E. Schwartz , Alessandro D. Santin a,⁎

    Article Title: Narrative review on the evolving role of HER2/neu targeting in uterine serous cancers
    Article Snippet: Tymon-Rosario et al ., 2021 ( ) , 12 USC cell lines , Thermo Fisher Scientific c-erbB-2 antibody , Modified 2007 ASCO/CAP; positive: 3+; equivocal 2+; negative: 0/1+ , 16.7% (2/12) , 25.0% (3/12) , , PathVysion HER2 DNA Probe Kit , Modified ASCO/CAP breast [2007] ( ) , 25.0% (3/12) , Not reported.

    Article Title: Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression
    Article Snippet: Briefly, HER2/neu immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2.
    Article Snippet: In the United States, epithelial ovarian (EOC), fallopian tube, and primary peritoneal cancer represent the leading cause of death from gynecologic malignancy.. In 2024, there will be a projected 19,680 new cases and 12,740 resultant deaths in the United States alone [1].. Due in part to a lack of adequate screening tests and non-specific symptoms, over two-thirds of ovarian, fallopian tube, or primary peritoneal cancers are diagnosed at an advanced/metastatic stage (III or IV) [2].

    Modification:

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of the cell blocks after deparaffinization and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific) at a 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.
    Article Snippet: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/ neu expression DennisMauricio , Stefania Bellone , LeventMutlu , BlairMcNamara , DiegoD.Manavella , CemDemirkiran , Miguel Skyler Z. Verzosa , Natalia Buza , Pei Hui , Tobias Max Philipp Hartwich , Justin Harold , Yang Yang-Hartwich , Margherita Zipponi , Gary Altwerger , Elena Ratner , Gloria S. Huang , Mitchell Clark , Vaagn Andikyan , Masoud Azodi , Peter E. Schwartz , Alessandro D. Santin a,⁎

    Article Title: Narrative review on the evolving role of HER2/neu targeting in uterine serous cancers
    Article Snippet: Tymon-Rosario et al ., 2021 ( ) , 12 USC cell lines , Thermo Fisher Scientific c-erbB-2 antibody , Modified 2007 ASCO/CAP; positive: 3+; equivocal 2+; negative: 0/1+ , 16.7% (2/12) , 25.0% (3/12) , , PathVysion HER2 DNA Probe Kit , Modified ASCO/CAP breast [2007] ( ) , 25.0% (3/12) , Not reported.

    Article Title: Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression
    Article Snippet: Briefly, HER2/neu immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2.
    Article Snippet: In the United States, epithelial ovarian (EOC), fallopian tube, and primary peritoneal cancer represent the leading cause of death from gynecologic malignancy.. In 2024, there will be a projected 19,680 new cases and 12,740 resultant deaths in the United States alone [1].. Due in part to a lack of adequate screening tests and non-specific symptoms, over two-thirds of ovarian, fallopian tube, or primary peritoneal cancers are diagnosed at an advanced/metastatic stage (III or IV) [2].

    Amplification:

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of the cell blocks after deparaffinization and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific) at a 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.
    Article Snippet: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/ neu expression DennisMauricio , Stefania Bellone , LeventMutlu , BlairMcNamara , DiegoD.Manavella , CemDemirkiran , Miguel Skyler Z. Verzosa , Natalia Buza , Pei Hui , Tobias Max Philipp Hartwich , Justin Harold , Yang Yang-Hartwich , Margherita Zipponi , Gary Altwerger , Elena Ratner , Gloria S. Huang , Mitchell Clark , Vaagn Andikyan , Masoud Azodi , Peter E. Schwartz , Alessandro D. Santin a,⁎

    Article Title: Narrative review on the evolving role of HER2/neu targeting in uterine serous cancers
    Article Snippet: Tymon-Rosario et al ., 2021 ( ) , 12 USC cell lines , Thermo Fisher Scientific c-erbB-2 antibody , Modified 2007 ASCO/CAP; positive: 3+; equivocal 2+; negative: 0/1+ , 16.7% (2/12) , 25.0% (3/12) , , PathVysion HER2 DNA Probe Kit , Modified ASCO/CAP breast [2007] ( ) , 25.0% (3/12) , Not reported.

    Article Title: Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression
    Article Snippet: Briefly, HER2/neu immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2.
    Article Snippet: In the United States, epithelial ovarian (EOC), fallopian tube, and primary peritoneal cancer represent the leading cause of death from gynecologic malignancy.. In 2024, there will be a projected 19,680 new cases and 12,740 resultant deaths in the United States alone [1].. Due in part to a lack of adequate screening tests and non-specific symptoms, over two-thirds of ovarian, fallopian tube, or primary peritoneal cancers are diagnosed at an advanced/metastatic stage (III or IV) [2].

    Over Expression:

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of the cell blocks after deparaffinization and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific) at a 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.
    Article Snippet: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/ neu expression DennisMauricio , Stefania Bellone , LeventMutlu , BlairMcNamara , DiegoD.Manavella , CemDemirkiran , Miguel Skyler Z. Verzosa , Natalia Buza , Pei Hui , Tobias Max Philipp Hartwich , Justin Harold , Yang Yang-Hartwich , Margherita Zipponi , Gary Altwerger , Elena Ratner , Gloria S. Huang , Mitchell Clark , Vaagn Andikyan , Masoud Azodi , Peter E. Schwartz , Alessandro D. Santin a,⁎

    Article Title: Narrative review on the evolving role of HER2/neu targeting in uterine serous cancers
    Article Snippet: Tymon-Rosario et al ., 2021 ( ) , 12 USC cell lines , Thermo Fisher Scientific c-erbB-2 antibody , Modified 2007 ASCO/CAP; positive: 3+; equivocal 2+; negative: 0/1+ , 16.7% (2/12) , 25.0% (3/12) , , PathVysion HER2 DNA Probe Kit , Modified ASCO/CAP breast [2007] ( ) , 25.0% (3/12) , Not reported.

    Article Title: Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression
    Article Snippet: Briefly, HER2/neu immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2.
    Article Snippet: In the United States, epithelial ovarian (EOC), fallopian tube, and primary peritoneal cancer represent the leading cause of death from gynecologic malignancy.. In 2024, there will be a projected 19,680 new cases and 12,740 resultant deaths in the United States alone [1].. Due in part to a lack of adequate screening tests and non-specific symptoms, over two-thirds of ovarian, fallopian tube, or primary peritoneal cancers are diagnosed at an advanced/metastatic stage (III or IV) [2].

    Expressing:

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of the cell blocks after deparaffinization and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific) at a 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody–Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression
    Article Snippet: Briefly, HER2 immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/neu expression.
    Article Snippet: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody–drug conjugate with topoisomerase I inhibitor payload, shows antitumor activity in uterine and ovarian carcinosarcoma with HER2/ neu expression DennisMauricio , Stefania Bellone , LeventMutlu , BlairMcNamara , DiegoD.Manavella , CemDemirkiran , Miguel Skyler Z. Verzosa , Natalia Buza , Pei Hui , Tobias Max Philipp Hartwich , Justin Harold , Yang Yang-Hartwich , Margherita Zipponi , Gary Altwerger , Elena Ratner , Gloria S. Huang , Mitchell Clark , Vaagn Andikyan , Masoud Azodi , Peter E. Schwartz , Alessandro D. Santin a,⁎

    Article Title: Narrative review on the evolving role of HER2/neu targeting in uterine serous cancers
    Article Snippet: Tymon-Rosario et al ., 2021 ( ) , 12 USC cell lines , Thermo Fisher Scientific c-erbB-2 antibody , Modified 2007 ASCO/CAP; positive: 3+; equivocal 2+; negative: 0/1+ , 16.7% (2/12) , 25.0% (3/12) , , PathVysion HER2 DNA Probe Kit , Modified ASCO/CAP breast [2007] ( ) , 25.0% (3/12) , Not reported.

    Article Title: Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression
    Article Snippet: Briefly, HER2/neu immunohistochemical staining was performed on paraffin-embedded 5 μm sections of cell blocks after deparaffinisation and rehydration, using the c-erbB-2 antibody (Thermo Fisher Scientific, Fremont, CA) at 1:800 dilution.

    Article Title: Trastuzumab deruxtecan (DS-8201a), a HER2-targeting antibody-drug conjugate, demonstrates in vitro and in vivo antitumor activity against primary and metastatic ovarian tumors overexpressing HER2.
    Article Snippet: In the United States, epithelial ovarian (EOC), fallopian tube, and primary peritoneal cancer represent the leading cause of death from gynecologic malignancy.. In 2024, there will be a projected 19,680 new cases and 12,740 resultant deaths in the United States alone [1].. Due in part to a lack of adequate screening tests and non-specific symptoms, over two-thirds of ovarian, fallopian tube, or primary peritoneal cancers are diagnosed at an advanced/metastatic stage (III or IV) [2].



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    Biogenex mouse monoclonal antibody directed against c-erbb-2 (her-2/neu
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    Monoclonal antibodies used

    Journal: Communications Biology

    Article Title: Predicting monoclonal antibody binding sequences from a sparse sampling of all possible sequences

    doi: 10.1038/s42003-024-06650-3

    Figure Lengend Snippet: Monoclonal antibodies used

    Article Snippet: TF3B5 , Aa 1242-1255 C-terminus human ErbB-2 (HER2), P04626 , PEYLGLD , None , ThermoFisher Cat# Ma5-13675.

    Techniques: Bioprocessing